Preheat the air fryer to 375°F (190°C) for 3–5 minutes. Line the basket or tray with parchment and spray lightly with oil.
Blend the cottage cheese until smooth.
A small blender or immersion blender works best for a creamy base.
Make the crust batter: In a bowl, whisk the egg, blended cottage cheese, flour, Parmesan, baking powder, garlic powder, onion powder, salt, and pepper until thick and spreadable.
Shape the base: Spread the batter on the parchment into a 7–8 inch round, about 1/4 inch thick. Keep edges even for uniform crisping.
Par-bake the crust in the air fryer for 6–8 minutes until set, lightly golden, and easy to lift with a spatula.
Add sauce and cheese: Spread pizza sauce thinly to the edges. Sprinkle mozzarella evenly.
Add turkey pepperoni or your favorite protein if using.
Air fry again for 4–6 minutes until the cheese melts and browns in spots and the edges look crisp.
Finish and serve: Let rest 2 minutes. Garnish with basil or red pepper flakes. Slice and enjoy warm.